The bill establishes a new section in Wyoming law that explicitly prohibits the jurisdiction of the United States Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) within the state. It states that any requirements, mandates, recommendations, instructions, or guidance from these organizations regarding COVID-19, including mask-wearing, vaccination, or medical testing, will not be binding or enforceable in Wyoming.

Additionally, the bill sets an effective date of July 1, 2024, for these provisions to take effect. This legislation aims to limit the influence of federal and non-governmental health organizations on public health policies in Wyoming.