Senate Resolution No. 429 designates October 2025 as Rett Syndrome Awareness Month in Texas, aiming to enhance understanding of this rare neurological disorder that predominantly affects females. Rett syndrome manifests in infants and toddlers, typically between 6 to 18 months, leading to a regression in motor skills and requiring lifelong assistance for daily activities. The condition is characterized by various impairments, including loss of speech and mobility, as well as distinctive repetitive hand movements. Recent biomedical research has shown promise in reversing neurological symptoms, with significant advancements in treatment, including the first FDA-approved therapy in 2023.

The resolution highlights the role of the International Rett Syndrome Foundation as a key advocate and funding source for research aimed at improving the quality of life for those affected by the disorder. By recognizing October 2025 as Rett Syndrome Awareness Month, the Texas Senate encourages all residents to educate themselves about Rett syndrome and support ongoing research and resources that can positively impact the lives of patients and their families.