Senate Resolution No. 429 designates October 2025 as Rett Syndrome Awareness Month in Texas, aiming to enhance understanding of this rare developmental disorder that predominantly affects females. Rett syndrome is characterized by the onset of symptoms in infants and toddlers, including the loss of motor skills, speech, and the ability to walk, along with other complications such as seizures and irregular breathing. The resolution highlights the importance of awareness and support for individuals with Rett syndrome, who require lifelong assistance.

The resolution also emphasizes the progress made in biomedical research, including the identification of the gene responsible for Rett syndrome in 1999 and the development of treatments, with the first FDA-approved therapy launched in 2023. It acknowledges the role of the International Rett Syndrome Foundation in funding research and advocating for policies that improve the quality of life for patients and their families. The Senate encourages all Texans to learn more about Rett syndrome during this awareness month to support ongoing research and resources for those affected by the condition.