H.R. No. 500 is a resolution recognizing March 21, 2025, as World Down Syndrome Day at the State Capitol of Texas. This day is significant as it highlights Down syndrome, a common chromosomal condition affecting approximately one in every 700 babies born in the United States. The resolution emphasizes the advancements in medical care that have improved the life expectancy of individuals with Down syndrome, bringing it closer to that of their peers without the condition. It also acknowledges the importance of quality education, supportive home environments, and community resources in enabling individuals with Down syndrome to lead fulfilling lives.

The resolution calls for all Texans to participate in World Down Syndrome Day, promoting a culture of respect and inclusion for those living with the condition. It recognizes the efforts of parents, medical professionals, and advocates who have worked tirelessly to secure the rights of individuals with Down syndrome, allowing them to live independently, access education and healthcare, and contribute to society. The United Nations General Assembly declared March 21 as World Down Syndrome Day in 2011, and this resolution aligns Texas with global efforts to raise awareness and foster inclusivity for individuals with Down syndrome.