The bill, S.B. No. 1645, mandates the Texas Tech University Health Sciences Center to conduct a comprehensive study on health, nutrition, physical activity, and chronic health issues in Texas. The study will utilize existing data from the past 50 years to analyze various factors, including dietary habits, substance consumption, physical activity levels, and the prevalence of chronic diseases across demographics. It will also evaluate best practices from "blue zones," assess trends in healthcare spending, and examine the economic impact of chronic diseases on healthcare costs and the overall economy. The study aims to prioritize Texas-specific data, with national data as a secondary option when necessary.

Additionally, the bill outlines that state agencies such as the Department of State Health Services and the Health and Human Services Commission must assist the health science center in this study. A report detailing the findings is required to be submitted by September 1, 2026, to the Health and Human Services Commission and relevant legislative committees. The act is set to take effect on September 1, 2025, and will expire on January 1, 2027.