S.J.R. No. 3 proposes a constitutional amendment to establish the Dementia Prevention and Research Institute of Texas, along with the creation of the Dementia Prevention and Research Fund. This initiative aims to allocate $3 billion from the state general revenue to support research, prevention, and treatment of dementia, Alzheimer's disease, Parkinson's disease, and related disorders. The Institute will be responsible for awarding grants to educational institutions, medical research facilities, and other entities to facilitate research and develop therapies, as well as to implement prevention programs.

The resolution outlines the governance structure of the Institute, including six-year terms for its decision-making body, and specifies the funding sources for the Dementia Prevention and Research Fund. It mandates that the fund be used exclusively for research, facility development, and operational costs related to dementia and related disorders. The proposed amendment will be presented to voters in an election scheduled for November 4, 2025, allowing the public to decide on the establishment of this significant health initiative in Texas.