The resolution proposes a constitutional amendment to establish the Dementia Prevention and Research Institute of Texas, which will oversee the creation of the Dementia Prevention and Research Fund. This fund is intended to support research, prevention, and treatment initiatives for dementia, Alzheimer's disease, Parkinson's disease, and related disorders. To facilitate this, the resolution includes a provision for the transfer of $3 billion from the state’s general revenue to the fund, which will be administered by the newly established institute. The fund will also be supported by additional appropriations, grants, and donations.

The amendment outlines the responsibilities of the institute, including awarding grants for research, supporting educational institutions and medical facilities, and establishing standards for the use of the fund. It also specifies that the fund will be used exclusively for research and development related to these diseases, as well as for operational costs of the institute. The proposed amendment will be presented to voters in an election scheduled for November 4, 2025, allowing the public to decide on the establishment of the institute and the associated funding.