The resolution proposes a constitutional amendment to establish the Dementia Prevention and Research Institute of Texas, which will oversee the creation of the Dementia Prevention and Research Fund. This fund is intended to finance research, prevention, and treatment initiatives related to dementia and similar disorders within the state. To support these efforts, the resolution includes a provision for the transfer of $3 billion from the state's general revenue to the fund, which will be administered by the newly established institute.

The amendment outlines the responsibilities of the institute, including awarding grants for research, supporting educational institutions, and ensuring proper oversight of the fund's usage. It also specifies that the fund will consist of various sources of revenue, including state appropriations, grants, and donations. The resolution mandates that the proposed amendment be presented to voters in an election scheduled for November 4, 2025, allowing the public to decide on the establishment of the institute and the associated funding.