S.B. No. 1351 is a legislative act that designates a specific portion of U.S. Highway 281 in Hidalgo County as the "U.S. Border Patrol Agent Jose Rodriguez-Lua Memorial Highway." The designated section runs between its intersections with Farm-to-Market Road 493 and Farm-to-Market Road 88. This new designation is intended to honor the contributions of Border Patrol Agent Jose Rodriguez-Lua and is established in addition to any existing designations for the highway.

The bill also mandates the Texas Department of Transportation to design and construct markers that indicate this new designation, as well as to erect a marker at each end of the highway and at appropriate intermediate sites along the route. The act is set to take effect on September 1, 2025, and includes a provision for renumbering to avoid multiple provisions with the same designation in the future.

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