H.R. No. 264 is a resolution recognizing March 17, 2025, as Profound Autism Awareness Day in Texas. It highlights the challenges faced by individuals with profound autism, a severe subtype of autism spectrum disorder characterized by significant intellectual disabilities and communication difficulties. The resolution notes that individuals with profound autism require constant supervision and assistance throughout their lives, often facing additional challenges such as being nonverbal, exhibiting self-injurious behaviors, and experiencing seizure disorders. The resolution also points out the demographic disparities among those affected, including a higher prevalence in females and individuals from minority and low socioeconomic backgrounds.

The resolution emphasizes the lack of adequate support and inclusion for people with profound autism and their caregivers, who often feel isolated due to the intensive care needs of these individuals. It calls for greater awareness and understanding of profound autism within the community, encouraging Texans to learn more about the condition and advocate for improved services and support for affected individuals and their families. The resolution was adopted by the Texas House of Representatives on March 13, 2025.