The resolution proposes a constitutional amendment to establish the Alzheimer's Prevention and Research Institute of Texas, which will be responsible for funding research and prevention efforts related to Alzheimer's disease and similar disorders. The amendment outlines the creation of the Alzheimer's Prevention and Research Fund, which will receive a transfer of $3 billion from the state's general revenue. This fund will be used to award grants for research, support institutions involved in Alzheimer's research, and develop programs aimed at mitigating the health impacts of the disease.

The resolution also details the governance structure of the institute, allowing members to serve six-year terms, and specifies the types of funding that can be utilized from the Alzheimer's Prevention and Research Fund. It mandates that grant recipients must have matching funds available and allows for the fund to cover operational expenses. The proposed amendment will be presented to voters in an election scheduled for November 4, 2025, allowing the public to decide on the establishment of the institute and the associated funding.