The resolution proposes a constitutional amendment to establish the Alzheimer's Prevention and Research Institute of Texas, which will oversee the creation of the Alzheimer's Prevention and Research Fund. This fund is intended to support research, prevention, and treatment of Alzheimer's disease and related disorders within the state. The amendment outlines the responsibilities of the institute, including awarding grants to educational and medical research institutions, supporting the development of therapies, and establishing standards for the proper use of the allocated funds.

To finance these initiatives, the resolution mandates a transfer of $3 billion from the state’s general revenue to the Alzheimer's Prevention and Research Fund, effective January 1, 2026. The fund will also receive additional appropriations, grants, and other income sources. The proposed amendment will be presented to voters in an election scheduled for November 4, 2025, allowing them to decide on the establishment of the institute and the associated funding.