House Bill 1492, also known as Senate Bill 2130, amends Tennessee Code Annotated, Title 15, Chapter 2, to establish October 1 of each year as "APDS Day." This day is designated to raise awareness for activated PI3K delta syndrome (APDS), a rare genetic immunodeficiency that affects approximately one to two individuals per million. The bill highlights the various challenges faced by those with APDS, including frequent infections, developmental delays, and a higher risk of certain cancers, while also emphasizing the importance of accurate diagnosis and genetic testing for affected individuals and their families.

The act aims to bring attention to the struggles of Tennesseans suffering from APDS and promote understanding of the condition within the community. It is set to take effect upon becoming law, with the public welfare necessitating its immediate implementation.