The bill S. 566, introduced in the South Carolina Senate, aims to declare May 5, 2025, as "Missing and Murdered Indigenous Women Red Dress Day" in the state. This resolution seeks to honor the lives of Indigenous women, girls, and Two-Spirit individuals who have been lost to violence, as well as those who are still missing. It highlights the national crisis of Missing and Murdered Indigenous Women, Girls, and Two-Spirit people (MMIWG2S), which disproportionately affects Native American communities, including in South Carolina. The resolution encourages citizens to wear red and participate in remembrance events to raise awareness and show solidarity with affected families.

Additionally, the resolution signifies the South Carolina Senate's commitment to addressing the MMIW crisis and working collaboratively with Tribal Nations, advocates, and state agencies to combat human trafficking and systemic injustices faced by Indigenous women and girls. This marks the first formal recognition of MMIW Red Dress Day by the South Carolina Senate, representing a significant step towards promoting Indigenous rights and protections. A copy of the resolution will be sent to relevant tribal entities, the Governor, and the South Carolina Commission for Minority Affairs.