The bill S. 544, introduced in the South Carolina Senate, aims to raise awareness about kidney disease, particularly focusing on APOL1-mediated kidney disease, which disproportionately affects individuals of African descent. The resolution encourages all South Carolinians to become more informed about kidney disease and specifically urges those with ancestry from Western and Central Africa to consider genetic testing for APOL1 gene mutations. It highlights the significant health disparities in kidney failure among African Americans and emphasizes the importance of early detection and proactive health measures to mitigate risks associated with kidney disease.

Additionally, the resolution designates Tuesday, April 29, 2025, as "APOL1-Mediated Kidney Disease Awareness Day" in South Carolina. It underscores the need for increased awareness and research into APOL1 genetic mutations to address the disparities in kidney disease and calls for better understanding and potential clinical trials for developing treatments for APOL1-mediated kidney disease.