The bill H. 4288, introduced in the South Carolina House of Representatives, aims to raise awareness about kidney disease, particularly APOL1-mediated kidney disease, which disproportionately affects individuals of African descent. It encourages South Carolinians to become more informed about kidney health and suggests that those with ancestry from Western and Central Africa consider genetic testing for APOL1 gene mutations, which can increase the risk of developing kidney disease. The resolution highlights the significant health disparities faced by African Americans regarding kidney failure and emphasizes the importance of early detection and proactive health measures.

Additionally, the bill designates Tuesday, April 29, 2025, as "APOL1-Mediated Kidney Disease Awareness Day" in South Carolina. It calls for increased awareness and research into APOL1 genetic mutations to better understand and address the disparities in kidney disease among populations. The resolution does not propose any new legal mandates but serves as a formal encouragement for education and awareness initiatives related to kidney health.