The bill H. 3506 aims to amend the South Carolina Code of Laws by adding Article 29 to Chapter 1, Title 1, which establishes definitions and rules of construction related to human biological sexes for the purposes of state laws, administrative regulations, and guidelines. It asserts that there are only two sexes, male and female, which correspond to specific biological characteristics and reproductive systems. The bill defines terms such as "woman," "man," "girl," and "boy," and clarifies that "gender" should be treated as synonymous with biological sex, while "gender identity" is not to be considered a substitute for sex or gender in legal contexts.

Additionally, the bill acknowledges the existence of individuals with disorders of sex development (DSD) and states that the definitions of "sex," "male," and "female" do not preclude reasonable accommodations for these individuals. The legislation emphasizes the intent to eliminate confusion surrounding the definitions of sex and related terms, asserting that separate facilities or sports leagues based on physical differences do not constitute unequal treatment under the law. The act will take effect upon approval by the Governor.