This bill amends Section 2-309I of Title 63 of the Oklahoma Statutes, which governs the prescription limits and rules for opioid drugs. Key changes include the authorization for practitioners to issue initial prescriptions for acute pain in divided quantities, which will count as a single prescription for regulatory purposes. The bill also clarifies that any opioid prescription for acute pain must be for the lowest effective dose of an immediate-release drug. Additionally, it establishes that practitioners may issue a subsequent prescription for acute pain after a minimum of seven days, provided certain conditions are met, including documentation of the necessity and appropriateness of the prescription.

The bill further emphasizes the importance of patient-provider agreements, particularly for patients under eighteen and those on long-term opioid therapy. It mandates that practitioners discuss the risks associated with opioid use, including addiction and overdose, and document these discussions in the patient's medical record. The legislation also outlines the requirements for monitoring patients on chronic opioid therapy, including regular assessments and efforts to reduce the potential for abuse. The act is set to take effect on November 1, 2026.