The bill establishes the "Barbara Weber Amyotrophic Lateral Sclerosis (ALS) Grant Program," which will be administered by the State Department of Health. The program aims to provide funding for research related to Amyotrophic Lateral Sclerosis (ALS) and to support Oklahoma residents affected by the disease, as well as those caring for family members with ALS. Starting July 1, 2026, the State Department of Health is required to submit an annual report detailing the number of grants awarded, the recipients, and the purposes of the funding.

Additionally, the bill creates the "Barbara Weber Amyotrophic Lateral Sclerosis (ALS) Grant Program Revolving Fund" within the Oklahoma State Treasury. This fund will be a continuous source of funding, consisting of appropriations, donations, and grants specifically designated for the ALS program. The bill appropriates $1,000,000 from the General Revenue Fund for the fiscal year ending June 30, 2026, to support the program's activities. The act is set to take effect on July 1, 2025, and includes an emergency clause for immediate implementation.