The bill establishes the "Barbara Weber Amyotrophic Lateral Sclerosis (ALS) Grant Program," which will be administered by the State Department of Health. The program aims to provide funding for research related to Amyotrophic Lateral Sclerosis (ALS) and to support Oklahoma residents affected by the disease, as well as those caring for family members with ALS. Starting July 1, 2026, the State Department of Health is required to submit an annual report detailing the number of grants awarded, the recipients, and the purposes of the funding to various state leaders.

Additionally, the bill creates the "Barbara Weber Amyotrophic Lateral Sclerosis (ALS) Grant Program Revolving Fund" within the Oklahoma State Treasury. This fund will be a continuous source of funding, not limited by fiscal year constraints, and will include all money received from appropriations, donations, and grants specifically for the program. The funds will be appropriated and can be budgeted and spent by the State Department of Health for the program's purposes. The act is set to take effect on July 1, 2025, and includes an emergency clause for immediate implementation upon passage.