The bill amends the Oklahoma State Athletic Commission Act to enhance the regulation of combative sports in the state. It grants the Oklahoma State Athletic Commission jurisdiction over the licensing of both amateur and professional combative sports practitioners, including mixed martial artists, kickboxers, and professional boxers. The Commission is authorized to stop unlicensed events and impose penalties on those promoting unsanctioned combative sports. Additionally, the bill removes certain exceptions regarding testing for human immunodeficiency virus (HIV) and hepatitis viruses, thereby strengthening health and safety regulations for participants. New definitions for roles within the industry, such as "promoter," "participant," and "vendor," are also introduced, emphasizing that participation in combative sports events requires Commission sanctioning.

Moreover, the bill updates the requirements for participants in amateur combative sports by mandating that applicants submit certified test results confirming they are not infected with HIV, hepatitis B, or hepatitis C, with testing required within 365 days prior to the contest. It allows for a medical statement confirming completion of hepatitis B vaccinations to substitute for test results for that virus. The bill also permits promoters to replace a participant within 24 hours of an event if the original participant cannot compete, provided the new participant meets testing requirements. The previous provision allowing a written agreement to waive licensure denial for late test results has been removed. The act is set to take effect on November 1, 2025.