The bill, known as the Jeff, Dave, and Angie Patient Right to Try Act, proposes the enactment of section 3792.08 of the Revised Code in Ohio, which outlines the conditions under which pharmacists, hospitals, and healthcare facilities may dispense drugs, including for off-label use, prescribed by physicians. It establishes definitions for key terms such as "health-related licensing board," "hospital," "in-house physician," and "off-label use." The bill specifies that a pharmacist must dispense a prescribed drug unless there are documented moral, ethical, or religious objections, or if the patient has a history of severe allergic reactions or contraindications. Additionally, it allows for the administration of drugs brought into a hospital by patients when certain conditions are met.

Furthermore, the bill protects healthcare professionals from disciplinary actions by licensing boards for prescribing or discussing off-label drug use, provided that the actions are not deemed reckless or grossly negligent. It emphasizes the importance of patient consent and the right to seek alternative treatment options if a hospital or facility is unwilling to prescribe a requested drug. However, the bill does not apply to controlled substances, drugs under risk evaluation strategies, or certain other specified categories, ensuring that existing laws regarding these substances remain intact.