House Memorial 42 recognizes the Virginia opossum, Didelphis virginiana, as an important native marsupial in New Mexico. The memorial highlights the ecological significance of opossums, noting their role in controlling pests such as ticks, insects, and rodents, as well as their adaptability to both rural and urban environments. It also emphasizes the unique advantages of their immune systems, including resistance to snake venom and a lower likelihood of contracting rabies.

The resolution calls for the Virginia opossum to be acknowledged as a vital part of New Mexico's diverse wildlife and encourages conservation awareness regarding this species. Additionally, it mandates that copies of the memorial be sent to the secretary of environment and the members of the New Mexico House of Representatives to promote awareness and support for the conservation of the Virginia opossum.