Requires the Commission for Public Health (Commission) to do the following no later than October 15, 2024. Requires the Commission to begin rulemaking to establish maximum contaminant levels (MCLs), as that term is defined under GS 130A-313 (the North Carolina Clean Water Act), for probable or known carcinogens and other toxic chemicals likely to pose a substantial hazard to public health.  Requires the Commission to establish MCL’s for the following five contaminants: (1) per- and poly-fluoroalkyl substances (PFAS); (2) perfluorooctanoic acid (PFOA); (3) perfluorooctane sulfonate (PFOS); (4) Hexavalent chromium (chromium-6); and (5)1,4-Dioxane. Also requires considering establishing MCLs for any other contaminants for which at least two other states have set MCLs or issued guidance.