The proposed bill establishes a psilocybin therapeutic use program in Minnesota for individuals aged 21 and older with qualifying medical conditions, emphasizing compassionate access, harm reduction, and patient safety. Key components include the creation of a registration system for patients, definitions related to the program, and the appointment of an advisory committee to assist in rulemaking. The bill outlines the responsibilities of the Commissioner of Health and the Commissioner of Agriculture in regulating the program, ensuring safety in cultivation and use, and mandates that cultivation occurs in secure locations at the primary residence of individuals. Registered patients can cultivate psilocybin for personal use or designate a cultivator, with specific possession and cultivation limits established by the commissioners.

Additionally, the bill includes provisions for the enrollment process, requiring certifications from healthcare practitioners and health screenings for contraindications. It establishes protections for registered patients, designated cultivators, and facilitators from civil or criminal penalties for actions permitted under the program. The legislation also emphasizes public education on responsible psilocybin use, introduces a Psychedelic Medicine Advisory Committee, and outlines data practices related to psilocybin. The bill aims to create a structured framework for the therapeutic use of psilocybin while ensuring patient safety, regulatory oversight, and compliance with established guidelines.