The bill amends existing legislation to appropriate funds for research into amyotrophic lateral sclerosis (ALS) and to support caregiver programs. Specifically, it allocates $20,000,000 for fiscal year 2023 and an unspecified amount for fiscal year 2024 from the general fund to the commissioner of the Office of Higher Education. This funding is designated for competitive grants aimed at advancing clinical and translational research related to ALS, with a focus on various research topics such as disease mechanisms and drug development. The commissioner is also tasked with submitting annual reports to the legislature detailing grant recipients, amounts awarded, and the outcomes of the funded research.

Additionally, the bill introduces a new appropriation for caregiver support programs, allocating an unspecified amount for fiscal year 2024 to the commissioner of human services for the Minnesota Board on Aging. This funding is intended to enhance caregiver support programs, specifically requiring that they include ALS-specific respite services. Both appropriations are characterized as onetime funding, with unencumbered balances not set to cancel until June 30, 2026.