The bill grants the city of Worcester the authority to adopt local general or zoning ordinances aimed at facilitating the development of large-scale institutional facilities. It specifically allows Worcester to require the creation of an Institutional Master Plan, which serves as a comprehensive land-use and development strategy for institutions within the city. This plan is intended to identify both existing and future growth, ensuring that the impacts of development are addressed through public review and adoption processes.

Additionally, the bill permits Worcester to impose a review process for Institutional Master Plans that regulates land use for various institutions, including hospitals, colleges, and non-profit educational organizations. It allows the city to issue special permits for these uses, which may have expiration and renewal requirements. Institutions that are already in existence at the time of the ordinance's adoption will need to apply for these special permits within 120 days. The act is set to take effect immediately upon passage.