House Bill No. 125, known as the "Louisiana Human Genomic Security Act of 2025," aims to protect individuals' genomic information from unauthorized access by foreign adversaries, specifically targeting entities from the People's Republic of China, Republic of Cuba, Islamic Republic of Iran, Democratic People's Republic of Korea, and the Russian Federation. The bill establishes a new chapter in the Louisiana Revised Statutes, detailing definitions related to genomic information, prohibiting the use of certain genetic sequencers and software produced by foreign adversaries, and restricting the storage of human genetic sequencing data to locations outside these countries. It also mandates that remote access to such data from these adversarial nations is prohibited.

The legislation imposes penalties for violations, with fines set at $10,000 per instance of non-compliance, as determined by the attorney general, who is granted sole authority to investigate and enforce these provisions. The bill emphasizes the importance of cybersecurity measures for the storage of genomic data and outlines the responsibilities of medical facilities and research entities in safeguarding this sensitive information. Overall, the bill seeks to ensure that American genetic information remains secure from foreign military and surveillance interests.