The bill establishes the Advanced Practice Registered Nurses (APRN) Compact, which facilitates interstate practice privileges for APRNs in participating states. It aims to streamline the licensure process by promoting uniform requirements and reducing duplicative regulations, thereby enhancing public safety and access to healthcare. Key provisions include the authority for states to take adverse actions against APRNs' multistate licenses, compliance with state practice laws where the patient is located, and a structured application process for multistate licenses that includes criminal background checks.

Additionally, the bill creates the Interstate Commission of APRN Compact Administrators to oversee the compact's administration, including rulemaking and financial operations. It outlines enforcement mechanisms, dispute resolution processes, and the conditions under which a state can withdraw from the compact. The commission is empowered to mediate disputes and enforce compliance, ensuring accountability among party states. The compact will take effect once seven states enact it, and it includes provisions for amendments and the maintenance of validity even if certain parts are deemed unconstitutional.