Provides that an automated tractor-trailer may not be operated on a highway to transport passengers or goods unless a human operator who meets all state and federal qualifications to operate a tractor-trailer is physically present in the automated tractor-trailer to monitor the performance of the automated tractor-trailer and to take control of all or part of the automated tractor-trailer's operation if necessary. Provides that an automated tractor-trailer operated in Indiana must meet federal motor vehicle standards and regulations.