Creates the Illinois Epstein Files Investigation Act. Establishes the Illinois Epstein Files Investigation Commission as an investigatory and advisory commission to investigate matters related to Jeffrey Epstein's network with a nexus to Illinois, facilitate enforcement of Illinois law, and promote transparency. Grants the Commission investigatory powers, including subpoena authority enforceable in circuit court, and requires referrals to the Attorney General and periodic reports to the Attorney General, Governor, and the General Assembly. Provides victim and whistleblower protections. Authorizes the Attorney General to exercise specified authority. Directs the Attorney General to share information upon request by the Commission. Ceases operation of the Commission after 5 years and repeals the Act after 6 years. Amends the Statewide Grand Jury Act to expand jurisdiction, to include human trafficking, involuntary servitude, sexual exploitation of children, permitting and failure to report sexual abuse of a child, prostitution-related offenses, patronizing a sexually exploited child, child pornography, bribery, official misconduct, solicitation of misconduct, tampering with public records, perjury, communicating with or harassment of jurors and witnesses, money laundering, obstruction of justice, and racketeering activity, but with a requirement for Attorney General certification or a requirement that offenses occur in more than one county or have a statewide nexus. Effective immediately.