Creates the 21st Century Diversity Business Act. Provides that the Department of Commerce and Economic Opportunity shall create and administer the 21st Century Diversity Business Program to provide loans and financial assistance to minority-owned businesses in 21st Century Diversity Business districts. Provides for application, eligibility, and loan requirements. Requires the Department and its grantees to provide technical assistance to businesses receiving loans through the Program. Requires the Department to enter into an agreement with businesses receiving loans through the Program with specified content. Requires the Office of the Secretary of State to make available to the public on the Internet website of the Office of the Secretary of State a registry of self-certified minority business owners from which both public and private entities may seek services. Provides further requirements concerning the registry. Provides for the adoption of rules.