The bill establishes a regulatory framework for kratom products in Iowa, requiring individuals or entities responsible for placing these products into commerce to register them annually with the Department of Health and Human Services. The registration application must include various certifications, such as compliance with federal good manufacturing practices, a statement of safety, and a certificate of analysis from an independent testing laboratory. The bill also mandates the creation of a database to maintain records of all registered kratom products. Additionally, it defines key terms related to kratom, including what constitutes a kratom product, kratom processor, and kratom food service establishment.

Furthermore, the bill imposes strict limitations on kratom products, prohibiting the sale of those containing certain harmful ingredients, and those that are attractive to children or intended for vaporization. It requires clear labeling on kratom products, including warnings against use by individuals under 21, pregnant or breastfeeding women, and a recommendation to consult healthcare professionals. Violations of the registration and sales provisions can result in significant penalties, including fines and potential imprisonment for serious offenses. The bill also outlines the enforcement mechanisms and the department's authority to revoke registrations if compliance is not met, ensuring the safety of kratom products and preventing their distribution to minors.