The PrEP DC Amendment Act of 2026 amends the Prohibition of Discrimination in the Provision of Insurance Act of 1986 to enhance protections for individuals using HIV prevention treatments, specifically pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP). The bill prohibits health benefit plans and insurers from considering an individual's use of HIV prevention treatment when making decisions about issuing disability, life, or long-term care insurance policies. Additionally, it prevents insurers from imposing cost-sharing, prior authorization, or medically unnecessary restrictions on HIV prevention services. The bill also establishes definitions for terms related to HIV prevention services and treatment, including baseline assessments and the roles of the Commissioner and Director of the Department of Health.

Furthermore, the bill creates the DC Health and Wellness Center Fund, which will collect revenue from insurance reimbursements and out-of-pocket payments for services provided at the DC Health and Wellness Center and affiliated clinics. The funds collected will be used exclusively for the operations of these centers and will not revert to the District's General Fund at the end of the fiscal year. The legislation aims to ensure that individuals have access to necessary HIV prevention services without facing discriminatory practices from insurers.